Tirzepatide Injection

In a 72-week randomized trial of adults with obesity, tirzepatide produced mean weight reductions of roughly 15 to 21 percent depending on dose, compared with about 3 percent on placebo.

  • Prescription Only
  • Compounded

Tirzepatide Injection

Compounded Tirzepatide Injection

$299/mo*

Duration

A dual agonist that activates two gut hormone receptors rather than one. GIP and GLP-1 work through different pathways, and tirzepatide engages both.

Supports
Appetite regulationWeight-management programsMetabolic support
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HSA/FSA reimbursable

HSA/FSA reimbursable

No Membership Required

No Membership Required

Licensed US Pharmacies

Licensed US Pharmacies

Compounded tirzepatide is not FDA-approved and is not equivalent to Zepbound or Mounjaro. Carries a boxed warning regarding thyroid C-cell tumors. Contraindicated in patients with personal or family history of medullary thyroid carcinoma or MEN 2. Prescription only; dispensed after medical evaluation.

Fast, discreet shipping

Unlimited follow-up with licensed physicians

In a 72-week randomized trial of adults with obesity, tirzepatide produced mean weight reductions of roughly 15 to 21 percent depending on dose, compared with about 3 percent on placebo.

TWO RECEPTORS

GLP-1 is one incretin hormone. Tirzepatide engages two.

Trial data from studies of the FDA-approved product.

Jastreboff et al., SURMOUNT-1, New England Journal of Medicine (2022)

Trial data from studies of the FDA-approved product. Compounded preparations are not FDA-approved and have not been evaluated in these trials.

HOW DUAL AGONISTS WORK

Two signals instead of one.

Glucose control.

Tirzepatide activates both the GIP and GLP-1 receptors. Both are incretin hormones the gut releases after a meal, and both are involved in insulin response, appetite signaling, and how quickly the stomach empties. Engaging both pathways is the pharmacologic distinction from single GLP-1 agonists.

Activates GLP-1 receptors

The GLP-1 pathway is associated with appetite suppression, glucose-dependent insulin release, and slowed gastric emptying.

Also activates GIP receptors

GIP is a separate incretin hormone with its own effects on insulin response and, based on preclinical work, on how fat tissue handles nutrients.

Slows gastric emptying

Food leaves the stomach more slowly, extending fullness after meals and moderating post-meal glucose rises.

Titrated upward over months

Dosing starts low and increases on a schedule to manage gastrointestinal side effects, which is why plans are structured across months.

HOW PEPTRA WORKS

From intake to your door in three to seven days

Prescription medicine from board-certified physicians, shipped to your door.

Medical intake

Step 1

Medical intake

Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.

A few minutes
Doctor review

Step 2

Doctor review

A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*

Within 72 hours
Fast shipping

Step 3

Fast shipping

Approved medications ship directly to your door in discreet packaging.

2-5 business days
Unlimited messaging

Step 4

Unlimited messaging

Your doctor is available via chat any time for additional support. Video consults available.

Up to 12 months

Prescription medicine from board-certified physicians, shipped to your door.

*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.

WHY PEPTRA MEDICINE

Precision medicine protocols to support longevity

  • Proactive care

    Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.

  • Transparent pricing

    No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.

  • Board-certified doctors

    Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.

  • Curated by longevity experts

    Every protocol is built by medical experts, based on longevity research from Our founder's science team.

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COMMON QUESTIONS

Questions, answered

What is compounded tirzepatide?

Compounded tirzepatide is a prescription injectable form of tirzepatide prepared by a licensed compounding pharmacy for an individual patient. It is not FDA-approved and is not the same as or equivalent to Zepbound or Mounjaro. Following shortage resolution (2024–2025), compounded tirzepatide may only be dispensed via an individual patient-specific prescription.

How does tirzepatide differ from semaglutide?

Semaglutide is a GLP-1 receptor agonist. Tirzepatide activates both GLP-1 and GIP receptors — a dual mechanism that clinical studies have shown can produce greater average weight reduction, though individual responses vary.

What are the side effects?

Gastrointestinal side effects (nausea, vomiting, diarrhea, constipation) are most common, especially during dose escalation. Tirzepatide carries a boxed warning for thyroid C-cell tumors; contraindicated in patients with personal or family history of medullary thyroid carcinoma or MEN 2.

Disclaimer: This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program.