Testosterone Cream

Randomized study of transdermal testosterone in hypogonadal men reported improvements in sexual function, mood, and body composition parameters alongside restoration of serum testosterone into the normal range.

  • FDA Approved
  • Controlled substance

Testosterone Cream

Topical Testosterone Cream

$129/mo*

Duration

Daily topical testosterone instead of weekly injections. Applied to the skin, absorbed steadily, and dosed by measurement rather than by schedule.

Supports
Daily transdermal TRT option
Get Started
HSA/FSA reimbursable

HSA/FSA reimbursable

No Membership Required

No Membership Required

Licensed US Pharmacies

Licensed US Pharmacies

Testosterone is FDA-approved and a Schedule III controlled substance. Prescribed only for clinically diagnosed low testosterone confirmed by lab testing. Telehealth prescribing permitted through December 31, 2026, subject to state law.

Fast, discreet shipping

Unlimited follow-up with licensed physicians

Randomized study of transdermal testosterone in hypogonadal men reported improvements in sexual function, mood, and body composition parameters alongside restoration of serum testosterone into the normal range.

STEADY VS PEAKS

Injections peak and fall. Daily topical holds a line.

Can transfer to others through skin contact

Wang et al., Journal of Clinical Endocrinology & Metabolism (2000)

Daily topical Weekly injection
Illustrates delivery patterns. Absorption through skin varies between individuals; dosing is adjusted against bloodwork.

HOW TOPICAL TESTOSTERONE WORKS

Absorbed daily, adjusted by bloodwork.

Glucose control.

Testosterone applied to the skin is absorbed into circulation over the course of the day, producing a steadier level than intermittent injection. The same physiology applies once it is in the bloodstream — the difference is the delivery pattern and the need to manage skin contact with others.

Steadier daily levels

Daily application avoids the peak-and-trough pattern of weekly injection, which some men find affects how they feel across the week.

No injections

For patients who would rather not inject, or cannot, topical delivery removes needles from the routine entirely.

Dosed against measured levels

Skin absorption varies, so the applied amount is adjusted based on follow-up bloodwork rather than set by a standard schedule.

Requires contact precautions

Wash hands after applying, cover the application site with clothing once dry, and avoid skin contact at that site with women and children.

HOW PEPTRA WORKS

From intake to your door in three to seven days

Prescription medicine from board-certified physicians, shipped to your door.

Medical intake

Step 1

Medical intake

Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.

A few minutes
Doctor review

Step 2

Doctor review

A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*

Within 72 hours
Fast shipping

Step 3

Fast shipping

Approved medications ship directly to your door in discreet packaging.

2-5 business days
Unlimited messaging

Step 4

Unlimited messaging

Your doctor is available via chat any time for additional support. Video consults available.

Up to 12 months

Prescription medicine from board-certified physicians, shipped to your door.

*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.

WHY PEPTRA MEDICINE

Precision medicine protocols to support longevity

  • Proactive care

    Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.

  • Transparent pricing

    No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.

  • Board-certified doctors

    Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.

  • Curated by longevity experts

    Every protocol is built by medical experts, based on longevity research from Our founder's science team.

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COMMON QUESTIONS

Questions, answered

How is the cream applied?

Typically applied to the inner thighs, upper arms, or scrotal skin once daily. Wash hands thoroughly after application and avoid skin-to-skin contact with partners or children until the site is dry.

Is testosterone cream as effective as injections?

Cream provides steady, daily absorption rather than the peaks and troughs of weekly injections. Effectiveness depends on consistent application and individual skin absorption, which varies.

Disclaimer: This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program.