Semaglutide Injection

In a 68-week randomized trial of adults with overweight or obesity, once-weekly semaglutide produced a mean body weight reduction of approximately 15 percent versus about 2.4 percent on placebo, alongside lifestyle intervention.

  • Prescription Only
  • Compounded

Semaglutide Injection

Compounded Semaglutide Injection

$199/mo*

Duration

A GLP-1 receptor agonist that supports appetite regulation and slows gastric emptying. Compounded with additional ingredients selected for the individual patient.

Supports
Appetite regulationWeight-management programs (as prescribed)Blood-sugar support
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HSA/FSA reimbursable

HSA/FSA reimbursable

No Membership Required

No Membership Required

Licensed US Pharmacies

Licensed US Pharmacies

Compounded semaglutide is not FDA-approved and is not equivalent to Wegovy or Ozempic. Carries a boxed warning regarding thyroid C-cell tumors. Contraindicated in patients with personal or family history of medullary thyroid carcinoma or MEN 2. Prescription only; dispensed after medical evaluation.

Fast, discreet shipping

Unlimited follow-up with licensed physicians

In a 68-week randomized trial of adults with overweight or obesity, once-weekly semaglutide produced a mean body weight reduction of approximately 15 percent versus about 2.4 percent on placebo, alongside lifestyle intervention.

WHY GLP-1s

The natural hormone lasts minutes. GLP-1 receptor agonists last days.

X-axis is not linear — intervals are not to scale.

Nauck & Meier, European Journal of Endocrinology (2019)

GLP-1 receptor agonists Native GLP-1
Illustrates the pharmacologic properties of the GLP-1 receptor agonist class. Not a comparison of specific products.

HOW GLP-1 RECEPTOR AGONISTS WORK

Supports feeling full for longer.

Glucose control.

Semaglutide is a GLP-1 receptor agonist that mimics a hormone the gut produces after eating. GLP-1 receptors are located in the brain, gut, and pancreas, where activation is associated with appetite regulation, insulin response, and the rate at which the stomach empties.

Activates GLP-1 receptors

The gut's own GLP-1 lasts one to two minutes. Receptor agonists are engineered to activate the same receptors for days, producing sustained rather than momentary signaling.

Signals satiety

GLP-1 receptors in the brain are involved in suppressing hunger signals and amplifying fullness signals after eating.

Slows gastric emptying

Food leaves the stomach more slowly, which extends the sensation of fullness after a meal and moderates the post-meal glucose rise.

Titrated upward over months

Dosing starts low and increases on a schedule. This is how gastrointestinal side effects are managed, and it is why the plan is structured across months.

HOW PEPTRA WORKS

From intake to your door in three to seven days

Prescription medicine from board-certified physicians, shipped to your door.

Medical intake

Step 1

Medical intake

Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.

A few minutes
Doctor review

Step 2

Doctor review

A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*

Within 72 hours
Fast shipping

Step 3

Fast shipping

Approved medications ship directly to your door in discreet packaging.

2-5 business days
Unlimited messaging

Step 4

Unlimited messaging

Your doctor is available via chat any time for additional support. Video consults available.

Up to 12 months

Prescription medicine from board-certified physicians, shipped to your door.

*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.

WHY PEPTRA MEDICINE

Precision medicine protocols to support longevity

  • Proactive care

    Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.

  • Transparent pricing

    No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.

  • Board-certified doctors

    Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.

  • Curated by longevity experts

    Every protocol is built by medical experts, based on longevity research from Our founder's science team.

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COMMON QUESTIONS

Questions, answered

What is compounded semaglutide?

Compounded semaglutide is a prescription injectable form of semaglutide prepared by a licensed compounding pharmacy for an individual patient. It is not FDA-approved and is not the same as or equivalent to Wegovy or Ozempic. Eligible patients receive it under a patient-specific prescription following a medical evaluation.

How is it administered?

Compounded semaglutide is given as a weekly subcutaneous injection. Your provider will guide you on self-injection technique, storage, and dose escalation.

What are the side effects?

The most common side effects are gastrointestinal: nausea, vomiting, constipation, or diarrhea, particularly when starting or increasing the dose. GLP-1 medications carry a boxed warning regarding thyroid C-cell tumors; contraindicated in patients with personal or family history of medullary thyroid carcinoma or MEN 2.

Is compounded semaglutide FDA-approved?

No. Following the resolution of the branded semaglutide shortage (2024–2025), compounded versions may only be dispensed via an individual patient-specific prescription with documented clinical need, through a licensed pharmacy.

Disclaimer: This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program.