Step 1
Medical intake
Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.
A few minutes
Two randomized, placebo-controlled phase 3 trials evaluated bremelanotide in premenopausal women with hypoactive sexual desire disorder and reported improvements in desire and reduced associated distress versus placebo.
PT-141 (Bremelanotide) Injection
Bremelanotide (PT-141) Injection
$249/mo*
Duration
PT-141 works in the brain rather than the bloodstream. Where ED medications improve blood flow, bremelanotide acts on melanocortin receptors involved in sexual desire itself.
Supports
Get Started
Sexual desireUsed as needed
HSA/FSA reimbursable
No Membership Required
Licensed US Pharmacies
PT-141 is administered before anticipated activity, with dosing frequency limits set by your provider. Nausea is the most common effect. Prescription only; dispensed after medical evaluation.
Fast, discreet shipping
Unlimited follow-up with licensed physicians
Two randomized, placebo-controlled phase 3 trials evaluated bremelanotide in premenopausal women with hypoactive sexual desire disorder and reported improvements in desire and reduced associated distress versus placebo.
DESIRE VS BLOOD FLOW
PDE5 inhibitors work below the belt. PT-141 works above the neck.
Trial data from studies of the FDA-approved product, in premenopausal women with HSDD.
Kingsberg et al., RECONNECT, Obstetrics & Gynecology (2019)
Trial data from studies of the FDA-approved product. Compounded preparations have not been evaluated in these trials.
HOW PT-141 WORKS
Acts on desire, not circulation.
Glucose control.
Bremelanotide is a synthetic peptide that activates melanocortin receptors, primarily MC4R, in the central nervous system. Those receptors sit in brain regions associated with sexual motivation, which is a different target from the peripheral vascular mechanism of PDE5 inhibitors like sildenafil and tadalafil.
Activates melanocortin receptors
PT-141 binds MC4R in the central nervous system, a pathway associated with sexual motivation rather than blood flow.
Independent of the vascular pathway
Because it does not act on cGMP or vascular smooth muscle, it addresses a different component of sexual response than ED medications.
Used before activity, not daily
Administered ahead of anticipated activity, with dosing frequency limits set by your provider.
Nausea is the common effect
Nausea is the most frequently reported side effect in the clinical trials and is usually most noticeable with the first few doses.
HOW PEPTRA WORKS
From intake to your door in three to seven days
Prescription medicine from board-certified physicians, shipped to your door.
Step 2
Doctor review
A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*
Within 72 hours
Step 3
Fast shipping
Approved medications ship directly to your door in discreet packaging.
2-5 business days
Step 4
Unlimited messaging
Your doctor is available via chat any time for additional support. Video consults available.
Up to 12 months
Prescription medicine from board-certified physicians, shipped to your door.
*Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.
WHY PEPTRA MEDICINE
Precision medicine protocols to support longevity
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Proactive care
Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.
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Transparent pricing
No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.
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Board-certified doctors
Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.
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Curated by longevity experts
Every protocol is built by medical experts, based on longevity research from Our founder's science team.
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COMMON QUESTIONS
Questions, answered
How is PT-141 different from ED medications?
When do I take it?
What's the most common side effect?
Disclaimer: This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program.